DOES SUBOPTIMAL HOUSEHOLD FLOORING INCREASE THE RISK OF DIARRHOEA AND INTESTINAL PARASITE INFECTION IN LOW AND MIDDLE INCOME ENDEMIC SETTINGS? A SYSTEMATIC REVIEW AND META-ANALYSIS PROTOCOL

Does suboptimal household flooring increase the risk of diarrhoea and intestinal parasite infection in low and middle income endemic settings? A systematic review and meta-analysis protocol

Abstract Background Water, sanitation, and hygiene interventions often fail to show long-term impact on diarrhoeal and/or intestinal parasite risk in many low- and middle-income countries.Less attention has been paid to wider contextual factors that may contribute to high levels of contamination in the domestic environment such as household floorin

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Trabectedin for advanced soft tissue sarcomas: optimizing use

Alison Reid, Juan Martin-Liberal, Charlotte Benson Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, UK Abstract: Patients with locally advanced or metastatic soft tissue sarcoma have a poor outlook with median survival in the order of 1 year.There is therefore an urgent need for novel agents to impact this disease.Trabectedin is one su

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